解沛忠教授
E-mail:peizhongxie@njtech.edu.cn;peizhongxie0216@163.com
1. 教育和研究经历:
2014.11-至今:新利18彩票讲师、副教授、教授
2013.07-2014.08:東京大学博士后(合作导师:Prof.Shū Kobayashi)
2008.09-2013.06:南开大学博士(导师:黄有教授)
2004.09-2008.07:聊城大学学士
2.科研和教学工作:
研究兴趣:绿色有机化学新反应探索及其机理研究;新型碱土金属催化体系设计以及脱水偶联反应研究;以生物活性分子骨架为导向的绿色有机合成。
学术成果和研究项目:迄今,在Nat. Commun.;Green Chem.; Org. Lett.; Chem. Commun.; Chem. Eur. J.; Adv. Synth. Catal.等期刊发表论文30余篇,申请发明专利10件(已获得授权4件)。部分研究成果被Nat. Rev.Chem.专文亮点评述,被中国科学报等报道,入选ESI高被引论文。获得第四届江苏省科协青年会员创新创业大赛决赛“三等奖”、“科创江苏”创新创业大赛决赛“三等奖”。主持国家自然科学基金青年基金、江苏省自然科学基金面上和青年基金,获得江苏省“六大人才高峰”高层次人才资助。
教学/指导学生:承担本科生《有机化学》,《有机合成进阶》等课程教学,获得“南工晨星奖教金”。指导的本科生获得江苏省优秀本科毕业论文“二等奖”和江苏省大学生创新创业优秀成果展示会“优秀论文奖”。指导的硕士研究生多人获得“国家奖学金”(付伟山/2019、李爽爽/2020、李博文/2021、邢慧聪/2021)。
3. 发表论文:
Publications @ NJ Tech
34.Xingying Cai, Huicong Xing, Ju Qiu, Bowen Li,Peizhong Xie*, Dehydrative Allylation of Alkenylsp2C-H Bonds,
Org. Lett.2021,23,4368.
33.Xiaobo Yang, Bowen Li, Huicong Xing, Ju Qiu,Teck-Peng Loh,Peizhong Xie*, Dehydrative allylation of P-H species under metal-free conditions,
Green Chem.2021,23, 1633.
32.Bowen Li, Wubing Zeng, Lin Wang, Zhishuang Geng, Teck-Peng Loh*,Peizhong Xie*, Visible-Light-Induced Trifluoromethylation of Allylic Alcohols,
Org. Lett.2021,23, 5253.
31.Shuangshuang Li, Ju Qiu, Bowen Li, Zuolian Sun,Peizhong Xie*,Teck-PengLoh*, Practical allylation with unactivated allylic alcohols under mild conditions,
Org. Chem. Front.2021,8, 3354.
30.Huicong Xing,Peizhong Xie*,Construction of Benzothiophene Fused Pyrrolidone in Water under Catalyst-Free Conditions,
Chin. J. Org. Chem.2021,41,431(Invitedhighlight article).
29.PeizhongXie*, Zuolian Sun, Shuangshuang Li, Xinying Cai, Ju Qiu, Weishan Fu, Cuiqing Gao, Shisheng Wu, Xiaobo Yang, Teck-Peng Loh*, Reciprocal-activation strategy for allylic sulfination with unactivated allylic alcohols,
Org. Lett.2020,22,4893.
28.PeizhongXie*, Zuolian Sun,ShuangshuangLi, Lei Zhang,XinyingCai, Weishan Fu, Xiaobo Yang, Yanan Liu, Xiangyang Wo,Teck-PengLoh*, Dehydrative cross-coupling of allylic alcohols with alkynes,
Org. Lett.2020,22, 1599.
27.Peizhong Xie*, Shuangshuang Li, Yanan Liu, Xinying Cai, Jinyu Wang, Xiaobo Yang, Teck-Peng Loh*, Alkaline-earth metal-catalyzed dehydrative allylic alkylation.
Org. Lett.2020,22, 31.
26.Peizhong Xie*, Xiangyang Wo, Xiaobo Yang, Xinying Cai, Shuangshuang Li, Cuiqing Gao, Weishan Fu, Zuolian Sun, Teck-Peng Loh*, Calcium-catalyzed regioselective dehydrative cross-coupling of propargylic alcohols with 1,3-dicarbonyl compounds,
Green Chem.2019,21, 5207.
25.Peizhong Xie*, Weishan Fu, Xinying Cai, Zuolian Sun, Ying Wu, Shuangshuang Li, Cuiqing Gao, Xiaobo Yang, Teck-Peng Loh*, A Ba/Pd catalytic system enables dehydrative cross-coupling and excellentE-selective wittig reactions,
Org. Lett.2019,21, 7055.
24.Peizhong Xie*, Weishan Fu, Ying Wu, Xinying Cai, Zuolian Sun, Shuangshuang Li, Cuiqing Gao, Xiaobo Yang, Teck-Peng Loh*, Allylic phosphorus ylides directly generated from alcohols with water as the only byproduct,
Org. Lett.2019,21, 4168.
23.Peizhong Xie*, Jinyu Wang, Yanan Liu, Jing Fan, Xiangyang Wo, Weishan Fu, Zuolian Sun, Teck-Peng Loh*, Water-promoted C-S bond formation reactions,
Nat. Commun.2018,9, 1321. (Highlighted by K. J. Geogheghan,Nat. Rev. Chem.2018, 2,3).
22.Yanan Liu,Peizhong Xie*, Zuolian Sun, Xiangyang Wo, Cuiqing Gao, Weishan Fu, Teck-Peng Loh*, Direct substitution of secondary and tertiary alcohols to generate sulfones under catalyst and additive-free conditions,
Org. Lett.2018,20, 5353.
21.Peizhong Xie*, Jing Fan, Yanan Liu, Xiangyang Wo, Weishan Fu, Teck-Peng Loh*, Bronsted acid/organic photoredox cooperative catalysis: Easy access to tri- and tetra-substituted alkenylphosphorus compounds from alcohols and P-H species,
Org. Lett.2018,20, 3341.
20.Xiangyang Wo,Peizhong Xie*, Weishan Fu, Cuiqing Gao, Yanan Liu, Zuolian Sun, Teck-Peng Loh*, Barium-catalyzed C-OH/P-H dehydrative cross-coupling for C-P Bond construction,
Chem. Commun.2018,54, 11132.
19.Peizhong Xie*, Jinyu Wang, Jing Fan, Yanan Liu, Xiangyang Wo, Weishan Fu, Teck-Peng Loh*, The C–OH/P–H dehydrative cross-coupling for the construction of the P–C bond under metalfree conditions,
Green Chem.2017,19, 2135.
18.Peizhong Xie*, Lei Guo, Lanlan Xu, Teck-Peng Loh*, Asymmetric P-C bond formation:diastereoselective synthesis of adjacent P,C-stereogenic allylic phosphorus compounds,
Chem. Asian J.2016,11, 1353.
17.Peizhong Xie, You Huang*, Morita-Baylis-Hillman adduct derivates (MBHADs): the versatile reactivity in Lewis base-promoted annulation,
Org. Biomol. Chem.2015,13,8578.(Review,ESIHighly Cited Paper).
Publications before independent career
16.Y. Yamashita, Y. Cui,P. Xie, S. Kobayashi, Zinc Amide Catalyzed RegioselectiveAllenylation and Propargylation of Ketones with Allenyl Boronate,
Org. Lett.2015,17, 6042.
15.P. Xie, E. Li, J. Zheng, Y. Huang*, Sequential Catalyst Phosphine/Secondary Amine Promoted [1+4]/Rearrangement Domino Reaction for the Construction of (2H)-Pyrans and 2-Oxabicyclo[2.2.2]oct-5-ene Skeletons,
Eur. J. Org. Chem.2014, 1189.
14.L. Liang, E. Li,P. Xie, Y. Huang,* Phosphine-Initiated Domino Reaction: A Convenient Method for the Preparation of Spirocyclopentanones,
Chem. Asian J.2014,9, 1270.
13.P. Xie, Y. Huang,* Cross-Rauhut-Currier Reactions Initiated Domino Annulations,
Eur. J. Org. Chem.2013, 6213.(Review, Invited by Editor)
12.P. Xie, E. Li, J. Zheng, Y. Huang,* R. Chen, Tunable Phosphine-Mediated Domino Reaction: Selective Synthesis of 2,3-Dihydrofurans and Biaryls,
Adv. Synth. Catal.2013,355, 161.(Hot Paper, Selected by Editor).
11.E. Li, Y. Huang*, L. Liang,P. Xie, Phosphine-Catalyzed [4 + 2] Annulation of γ-Substituent Allenoates: Facile Access to Functionalized Spirocyclic Skeletons,
Org. Lett.2013,15, 3138.
10.E. Li,P. Xie, L. Yang, L. Liang, Y. Huang,* Tuning Catalysts to Tune the Products: Phosphine-Catalyzed Aza-Michael Addition Reaction of Hydrazones with Allenoates,
Chem. Asian J.2013,8, 603.
9.P. Xie, Y. Huang,* R. Chen, Phosphine-Mediated Domino Benzannulation Strategy for the Construction of Highly Functionalized Multiaryl Skeletons,
Chem. Eur. J.2012,18,7362.(Most Accessed in May 2012, Top 10)
8.P. Xie,W. Lai, Z. Geng, Y. Huang,* R. Chen, Phosphine-Catalyzed Domino Reaction for the Synthesis of Conjugated 2,3- Dihydrofurans from Allenoates and Nazarov Reagents,
Chem. Asian J.2012,7,1533.
7.L. Yang,P. Xie, E. Li, X. Li, Y. Huang,* R. Chen,Phosphine-catalyzed domino reaction: an efficient method for the synthesis of highly functionalized spiro[furan-indoline]diones,
Org. Biomol. Chem.2012, 10, 7628.
6.X. Meng,P. Xie, Y. Huang,* R. Chen,Organocatalytic domino reaction of salicyl N-thiophosphoryl imines and methyl vinyl ketone initiated by an aza-MBH reaction with bifunctional phosphine catalysts,
RSC Adv.2012,2, 8104.
5.P. Xie#,L. Wang#, L. Yang, E. Li, J. Ma, Y. Huang,* R. Chen, Domino Reaction for the Chemo- and Stereoselective Synthesis oftrans-2,3-Dihydrobenzofurans fromN-Thiophosphinyl Imines and Sulfur Ylides,
J. Org. Chem.2011,76, 7699. (#Equal contribution)
4.P. Xie, Y. Huang,* W. Lai, X. Meng, Ruyu Chen, Bifunctional Phosphine -catalyzedcross-Rauhut–Currier/Michael/AldolCondensation Triple Domino Reaction: Synthesis of Functionalized Cyclohexenes,
Org. Biomol. Chem.2011,9, 6707.
3.J. Ma,P. Xie, C. Hu, Y. Huang,* R. Chen,Substrate-Controlled, Phosphine-Catalyzed Domino Reactions of Activated Conjugated Dienes: Highly Diastereoselective Synthesis of Bicyclic Skeletons,
Chem. Eur. J.2011,17,7418.
2.P. Xie,Y. Huang,* R. Chen,* Phosphine-Catalyzed Domino Reaction: Highly Stereoselective Synthesis oftrans-2,3-Dihydrobenzofurans from SalicylN-Thiophosphinyl Imines and Allylic Carbonates,
Org. Lett.2010,12, 3768-3771.
1.X. Meng, Y. Huang*, H. Zhao,P. Xie, J. Ma, R. Chen, PPh3-Catalyzed Domino Reaction: A Facile Method for the Synthesis of Chroman Derivatives,
Org. Lett.2009,11, 991.