个人简历
1989-1994美国哈佛大学,化学系,博士 1994-1999新加坡国立大学,助理教授 1999-2004新加坡国立大学,副教授 2004-2005新加坡国立大学,教授 2005-2008新加坡南洋理工大学,终身教授,化学与生物系,系主任 2008-2012新加坡南洋理工大学,物理与数学科学学院,副院长 2005-新加坡南洋理工大学,终身教授
罗德平教授,国际著名化学家,新加坡科学院院士、马来西亚科学院院士,原新加坡化学学院建院院长。
研究方向
绿色化学;不对称有机合成反应;生物质分子的有机转化;有机合成化学新反应、新概念的研究;具有生物活性的复杂天然产物和药物的全合成研究。
学术成绩
2017 Yoshida prize(International Organic Chemistry Foundation) 2017 Assoc. Editor of The Journal of Organic Chemistry
2004-Present Advisory board member of Chem. Commun.; Synlett.; Synthesis; ChemCatChem; Heterocycles and etc.;Assoc. Editor of Asian Journal of Chemistry.
2014 Fellow, Royal Society of Chemistry ( RSC). 2010 Fellow, Academia of Sciences, Malaysia.
2010 GSK-SNIC Award in Organic Chemistry.
2010 Excellence Teaching Award, School of Physical and Mathematic Science (SPMS), NTU.
代表性论文
1. Jiang, B.; Zhao, M.; Li, S.-S; Xu, Y.-H.;Loh, T.-P.Macrolide Synthesis trough Intramolecular Oxidative Cross-Coupling of Alkenes,Angew.Chem. Int. Ed.2017, DOI: 10.1002/anie.201710601. 2. Liang, Q.-J.; Yang, C.; Meng, F.-F.; Jiang, B.; Xu, Y.-H.;Loh, T.-P.Chelation versus Non-Chelation Control in the Stereoselective Alkenyl sp2C-H Bond Functionalization Reaction.Angew. Chem. Int. Ed.2017, 129, 5173. 3. Shen, L.; Zhao, K.; Doitomi, K.; Ganguly, R.; Li, Y.-X. Shen, Z.-L; Hirao, H.;Loh, T.-P.Lewis Acid-Catalyzed Selective [2 + 2]-Cycloaddition and Dearomatizing Cascade Reaction of Aryl Alkynes with Acrylates.J. Am. Chem. Soc.2017,139, 13570. 4. Lan, Y.; Chang,X.-H.; Fan, P.; Shan,C.-C. Liu, Z.-B.;Loh, T.-P.; Xu,Y.-H.Copper-Catalyzed Silylperoxidation Reaction of α,β-Unsaturated Ketones, Esters, Amides, and Conjugated Enynes.ACS. Catal.2017,7, 7120. 5. Zhao, K.; Shen, L.; Shen, Z.-L.;Loh, T.-P.Transition metal-catalyzed cross-coupling reactions using organoindium reagents.Chem. Soc. Rev.2017,46, 586. 6. Wang, C.-Q.; Ye, L.; Feng, C.;Loh, T. -P.C-F Bond Cleavage Enabled Redox-Neutral [4+1] Annulation via C-H Bond Activation,J. Am. Chem. Soc.2017,139, 1762. 7. Tian, P.; Wang, C.-Q.; Cai, S.-H.; Song, S.; Ye, L.; Feng, C.;Loh, T. -P.Fˉ Nucleophilic-Addition-Induced Allylic Alkylation,J. Am. Chem. Soc.2016,138, 15869. 8. Cai, S.-H.; Xie, J.-H.; Ye, L.; Feng, C.;Loh, T. -P.isible-Light-Promoted Carboimination of Unactivated Alkenes for the Synthesis of Densely Functionalized Pyrroline Derivatives,ACS Cat.2016,6, 5571. 9. Hu, X.-H.; Yang, X.-F.;Loh, T.-P.Selective Alkenylation and Hydroalkenylation of Enol Phosphates through Direct C-H Functionalization.Angew. Chem. Int. Ed.2015,127, 15755. 10. Lu, M.-Z.; Wang, C.-Q.;Loh, T.-P.Copper-Catalyzed Vicinal Oxyazidation and Diazidation of Styrenes under Mild Conditions: Access to Alkyl Azides.Org. Lett.2015,17, 6110. 11. Wang, M.; Liu, Z.-L.; Zhang, X.; Tian, P.-P.; Xu, Y.-H.;Loh, T.-P.Synthesis of Highly Substituted Racemic and Enantioenriched Allenylsilanes via Copper-Catalyzed Hydrosilylation of (Z)-2-Alken-4-ynoates with Silylboronate.J. Am. Chem. Soc.2015,137, 14830. 12. Zhou, J.-H.; Jiang, B.; Meng, F.-F.; Xu, Y.-H.;Loh, T.-P.B(C6F5)3: A New Class of Strong and Bulky Lewis Acid for Exo-Selective Intermolecular Diels–Alder Reactions of Unreactive Acyclic Dienes with α,β-Enals.Org. Lett.2015,17, 4432. 13. Zhang, M.-X.; Hu, X.-H.; Xu, Y.-H.;Loh, T.-P.Selective Dealkylation of Alkyl Aryl Ethers.Asian J. Org. Chem.2015,4, 1047. 14. Qiu, S.-Q.; Xu, Y.-H.;Loh, T.-P.Palladium-Catalyzed Intermolecular Oxyarylation of Vinylacetates with Retention of an Alkenyl Moiety.Org. Lett.2015,17, 3462. 15. Lu, P.; Feng, C.;Loh, T.-P.Divergent Functionalization of Indoles with Acryloyl Silanes via Rhodium-Catalyzed C-H Activation.Org. Lett.2015,17, 3210. 16. Chen, Y.-C.; Zhu, M.-K.;Loh, T.-P.Csp3–Csp3Bond Cleavage in the Palladium-Catalyzed Aminohydroxylation of Allylic Hydrazones Using Atmospheric Oxygen as the Sole Oxidant.Org. Lett.2015,17,2712. 17. Zhang, X.; Wang, M.; Ding, R.; Xu, Y.-H.;Loh, T.-P.Highly Enantioselective and Anti-Diastereoselective Catalytic Intermolecular Glyoxylate–Ene Reactions: Effect of the Geometrical Isomers of Alkenes.Org. Lett.2015,17,2736. 18. Koh, P.-F.;Loh, T.-P.Synthesis of biologically active natural products, aspergillides A and B, entirely from biomass derived platform chemicals.Green Chem.2015,17,3746. 19. Tian, P.; Feng, C.;Loh, T.-P.Rhodium-catalysed C(sp2)-C(sp2) bond formation via C-H/C-F activation.Nat. Commun.2015,6, 7472. 20. Tian, P.-P.; Cai, S.-H.; Liang, Q.-J.; Zhou, X.-Y.; Xu, Y.-H.;Loh, T.-P.,Palladium-Catalyzed Difunctionalization of Internal Alkynes via Highly Regioselective 6-Endo Cyclization and Alkenylation of Enynoates: Synthesis of Multisubstituted Pyrones.Org. Lett.2015,17,1636. 21. Isobe, M.; Nishida, A.; Choo, Y.-M.; Rahman, N. A.; Ploypradith, P.; Ruchirawat, S.; Lin, G.-Q.; Li, A.; Yao, Z.-J.; Uang, B.-J.; Liao, C.-C.; Chiu, P.; Kim, B. M.;Loh, T.-P.,The Last and Next Decades of the Asian Core Program on Cutting-Edge Organic Chemistry in Asia.Chem. Asian J.2015,10,790. 22. Yang, X.-F.; Hu, X.-H.;Loh, T.-P.,Expedient Synthesis of Pyrroloquinolinones by Rh-Catalyzed Annulation of N-Carbamoyl Indolines with Alkynes through a Directed C–H Functionalization/C–N Cleavage Sequence.Org. Lett.2015,17,1481. 23. Pankajakshan, S.; Chng, Z. G.; Ganguly, R.;Loh, T.-P.,Copper-catalyzed aerobic carboxygenation and N-arylation of [1,2,3]triazolo[1,5-a]pyridines towards pyridinium triazolinone ylides.Chem. Commun.2015,51,5929. 24. Zhang, L.-Y.; Zhou, J.-H.; Xu, Y.-H.;Loh, T.-P.,Copper-Catalyzed Enantioselective Conjugate Addition of Grignard Reagents to Methyl 4,4,4-Trifluorocrotonate: Synthesis of Enantioenriched Trifluoromethylated Compounds.Chem. Asian J.2015,10,844. 25. Zhang, S.; Li, L.; Hu, Y.; Zha, Z.; Wang, Z.;Loh, T.-P., Bifunctional Amino Sulfonohydrazide Catalyzed Direct Asymmetric Mannich Reaction of Cyclic Ketimines with Ketones: Highly Diastereo- and Enantioselective Construction of Quaternary Carbon Stereocenters.Org. Lett.2015,17,1050. 26. Hu, X.-H.; Zhang, J.; Yang, X.-F.; Xu, Y.-H.;Loh, T.-P., Stereo- and Chemoselective Cross-Coupling between Two Electron-Deficient Acrylates: An Efficient Route to (Z,E)-Muconate Derivatives.J. Am. Chem. Soc.2015,137,3169. 27. Yang, X.-F.; Hu, X.-H.; Feng, C.;Loh, T.-P., Rhodium(iii)-catalyzed C7-position C-H alkenylation and alkynylation of indolines.Chem. Commun.2015,51, 2532. 28. Wang, M.; Zhang, X.; Zhuang, Y.-X.; Xu, Y.-H.;Loh, T.-P., Pd-Catalyzed Intramolecular C–N Bond Cleavage, 1,4-Migration,sp3C–H Activation, and Heck Reaction: Four Controllable Diverse Pathways Depending on the Judicious Choice of the Base and Ligand.J. Am. Chem. Soc.2015,137, 1341. 29. Cheng, J.-K.;Loh, T.-P.Copper- and Cobalt-Catalyzed Direct Coupling of sp3 α-Carbon of Alcohols with Alkenes and Hydroperoxides.J. Am. Chem. Soc.2015,137, 42. 30. Feng, C.; Feng, D.;Loh, T.-P. Rhodium(iii)-catalyzed C-H allylation of electron-deficient alkenes with allyl acetates.Chem. Commun.2015,51,342.
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罗德平 教授 Email:teckpeng@njtech.edu.cn |