余昌敏 ▍YU Chang-Min-新利18彩票柔性电子（未来技术）学院

余昌敏，教授，博士生导师

生物电子材料研究所所长

联系方式

课题组主页：https://www.x-mol.com/groups/yuchangmin

办公地点：南京市新模范马路5号，新利18彩票丁家桥校区科创D楼1602

联系电话：+86-15820250571

Email：iamcmyu@njtech.edu.cn

学习工作经历

2018.04至今：新利18彩票，柔性电子（未来技术）学院&先进材料研究院，教授

2013.12 - 2016.01：新加坡国立大学，化学系，博士后

2013.08 - 2017.12：华南理工大学，材料学院，讲师

2008.09 - 2013.07：华南理工大学，材料学专业，博士

2004.09 - 2008.07：安徽大学，高分子材料专业，学士

研究方向

（1）柔性生物电子传感器开发及应用

（2）有机荧光分子探针合成及生物成像

（3）活性药物分子智能递送体系构建

主要学术成绩

课题组主要从事柔性生物电子材料的开发和应用。面向临床疾病的诊疗需求，结合柔性生物电子和有机电子技术前沿，解决电子器件在疾病诊疗中的关键科学问题，为生物有机电子在健康医疗中的应用提供新的思路。迄今在Adv. Mater., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Allergy, Adv. Healthc. Mater., Small等国际期刊上发表SCI论文80余篇。其中，2篇代表作被评为“ESI高被引论文”，论文总被引3500余次，H-index 31。申请/授权专利20余件。先后入选南京市留学人员科技创新人才项目（2019）、“创业浦口”英才计划团队（2020）和“南太湖精英计划”领军型创新创业团队（2022）。已主持省部级及以上项目10余项。指导研究生多次获得校优秀毕业生、国家奖学金、时钧奖学金等。课题组毕业生主要进入国内外高校读博和巴斯夫、药明康德、药石等知名企业工作。热烈欢迎有化学、材料和生物背景的同学加入课题组，共同进步！

近期代表性论文

1. Yue Wu^#, Zhongting Zhao^#, Naidi Yang^#, Chenqi Xin, Zheng Li, Jiajia Xu, Bo Ma, Kah-Leong Lim, Lin Li, Qiong Wu*,Changmin Yu*, Chengwu Zhang.* Vitamin B12 ameliorates the pathological phenotypes of multiple Parkinson's disease models by alleviating oxidative stress.Antioxidants,2022, 11, x. https://doi.org/10.3390/xxxxx

2. Lihua Huang, Bicong Zhou,Changmin Yu*, Qian Shen, Zhongxi Huang, Qiong Wu, Naidi Yang, Lin Li*, and Wei Huang*. Ultrastable gold nanoparticles-based nanoplatform with mitochondria targeting and high-fidelity intracellular bioimaging enterokinase levels.Sens. Actuators B, 2022, 372, 132666.

3. Qianhui Qi^#, Jiaying Geng^#, Weizhen An, Qiong Wu, Nan Wang, Yu Zhang, Xue Li, Qian Shen*, Wei Wang*,Changmin Yu*, and Lin Li*.Stimulus-Responsive Degradation of Silica Nanoparticles for Biomedical Applications: From the Degradation Behavior to Mechanism. 2022, preparing.

4. Chenhan Wang^#, Duoteng Zhang^#, Haiyan Yang^#, Liang Shi, Lin Li, Changmin Yu*, Jifu Wei*, Qiang Ding*.A light-activated magnetic bead strategy utilized in spatio-temporal controllable exosomes isolation.Front. Bioeng. Biotechnol. 2022, 10, 1006374.

5. Xiaojing Ling^#, Yongxin Liu^#, Danxuan Zhu^#, Weizhen An, Jiaying Geng, Lin Li,Changmin Yu*, Jifu Wei*.Colorimetric visualization of histamine secreted by basophils based on DSP-functionalized gold nanoparticles.Anal. Methods, 2022, 14 (27), 2698-2702.

6.Changmin Yu^#, Shuangxi Wang^#, Chenchen Xu^#, Yang Ding, Gaobin Zhang, Naidi Yang, Qiong Wu, Qicai Xiao, Limin Wang, Bin Fang, Chibin Pu, Jingyan Ge, Liqian Gao, Lin Li,* and Shao Q. Yao.* Two-photon small-molecule fluorogenic probes for visualizing endogenous nitroreductase activities from tumor tissues of a cancer patient.Adv. Healthcare Mater. 2022, 2200400.

7. Lihua Huang, Zonghao Sun, Qian Shen, Zhongxi Huang, Shuangxi Wang, Nai-di Yang, Gongqiang Li, Qiong Wu*, Wei Wang*, Lin Li,Changmin Yu*. Rational design of nanocarriers for mitochondria-targeted drug delivery.Chin. Chem. Lett., 2022, 33(9), 4146-4156.

8. Yongxin Liu^#, Mengda Cao^#, Zhongxi Huang^#,Changmin Yu*, Nai-Di Yang, Qiong Wu, Wenjie Duan, Yi Zhu, Ji-Fu Wei*, Li Lin*, Wei Huang.Ultrasensitive detection of IgE levels based on magnetic nanocapturer linked immunosensor assay for early diagnosis of cancer.Chin. Chem. Lett., 2022, 33(4), 1855-1860.

9. Xingwei Chen^#, Zhongxi Huang^#, Lihua Huang, Qian Shen, Nai-Di Yang, Chibin Pu*, Jinjun Shao*, Lin Li,Changmin Yu*, Wei Huang.Small-molecule fluorescent probes based on covalent assembly strategy for chemoselective bioimaging.RSC Adv., 2022, 12(3), 1393-1415.

10. Bicong Zhou^#, Xiaolu Guo^#, Naidi Yang*, Zhongxi Huang, Lihuang, Huang, Zhijie Fang, Chengwu Zhang, Lin Li,Changmin Yu*.Surface engineering strategies of gold nanomaterials and their applications in biomedicine and detection.J. Mater. Chem. B, 2021, 9 (28), 5583-5598.

11. Jie Li,^#Zhe Su,^#Changmin Yu*, Yan Yuan, Qiong Wu, Jie Liu, Bo Peng, Wenbo Hu, Xiaomei Lu*, Haidong Yu, Lin Li*, Wei Huang.Recent progress in the development of sensing systems for in vivo detection of biological hydrogen sulfide.Dyes and pigments,2021, 192, 109451.

12. Mengda Cao^#, Yongxin Liu^#, Chen Lu^#, Miao Guo, Lin Li,Changmin Yu*, Ji-Fu Wei*.Ultrasensitive detection of specific IgE based on nanomagnetic capture and separation with AuNP-anti-IgE nanobioprobe for signal amplification.Anal. Methods, 2021, 13 (22), 2478-2484.

13. Mengda Cao^#, Xisi Han^#, Chen Lu^#, Yujie Wang, Zhiqiang Xu, Shuangxi Wang, Bicong Zhou, Chengwu Zhang,Changmin Yu*, Lin Li*, Ji-Fu Wei*.A novel method for precise detection of allergen-specific IgE via immobilizing His-tagged allergens to paper-based device.Allergy, 2021, 76(2), 567-571.

14. Xisi Han^#, Mengda Cao^#, Bicong Zhou^#,Changmin Yu*, Yongxin Liu, Bo Peng, Ling Meng, Ji-Fu Wei*,Lin Li*, Wei Huang. Specifically immobilizing His-tagged allergens to magnetic nanoparticles for fast and quantitative detection of allergen-specific IgE in serum samples.Talanta, 2020, 219, 121301.

15. Qian Shen^#, Shuangxi Wang^#, Nai-Di Yang, Chengwu Zhang, Qiong Wu*, Changmin Yu*.Recent development of small-molecule organic fluorophores for multifunctional bioimaging in the second near-infrared window.J. Lumin. 2020, 225, 117338.

16. Duoteng Zhang,^#Wei Du,^#Bo Peng,* Yun Ni, Haixiao Fang, Xinghan Qiu, Gaobin Zhang, Qiong Wu,Changmin Yu,* Lin Li,* Wei Huang. Two-photon small molecular fluorogenic probe visualizing biothiols and sulfides in living cells and zebrafishes.Sensors Actuat. B-Chem., 2020, 323, 128673.

17. Xingwei Chen,^#Jiajia Xu,^#Fengtai Suo,^#Changmin Yu,* Duoteng Zhang, Jian Chen, Qiong Wu, Su Jing,* Lin Li,* Wei Huang.A novel naphthofluorescein-based probe for ultrasensitive point-of-care testing of zinc(II) ions and its bioimaging in living cells and zebrafishes.Spectrochim.Acta A. 2020, 229, 117949.

18. Shuangxi Wang, Bicong Zhou, Na Wang,Changmin Yu*, Nai-Di Yang, Jian Chen, Qiong Wu, Chengwu Zhang, Lin Li*, Wei Huang.Mitochondria-targeted fluorescent probe based on vibration-induced emission for real-time monitoring mitophagy-speciﬁc viscosity dynamic.Chin. Chem. Lett., 2020, 31(11), 2897-2902.

19. Hong Wang^#, Jing Wei^#, Chonghua Zhang*, Yuan Zhang, Yubin Zhang, Lin Li, Changmin Yu*, Peisheng Zhang, Jian Chen*.Red carbon dots as label-free two-photon fluorescent nanoprobes for imaging of formaldehyde in living cells and zebrafishes.Chin. Chem. Lett., 2020, 31(3), 759-763.