邀请人: 余昌敏 教 授
报告地点:科技创新大楼C501室
Precise measurement of enzyme activity in living systems with molecular imaging probes is becoming an important technique to unravel the functional roles of different enzymes in biological processes. Activatable probes whose imaging signal can be specifically switched from the “off” to “on” state upon interaction with a target of interest, are particularly attractive due to their improved sensitivity and specificity. In this talk, I will introduce the recent studies of development of activatable probes in our group, and highlight their applications for multimodality imaging (fluorescence, MRI and PET) of protease activity in living cells and animals.
叶德举,南京大学化学化工学院教授,博士生导师,中组部重要人才计划青年项目入选者(2015年)。2004年从南京大学化学化工学院获得学士学位,2009年在中科院上海药物所获博士学位;2009年-2014年9在美国斯坦福大学医学院分子影像学中心进行博士后研究。2014年10月聘任南京大学化学化工学院副教授,2015年6月聘任南京大学教授。主要从事多模态分子影像探针设计、活性检测以及动物活体成像研究。