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朱亦龙
阅读次数:发布时间:2023-05-24

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朱亦龙,副教授,硕士生导师。

2017年在新利18彩票 获得工学博士学位;201712月至201812月在美国Texas Tech University从事博士后研究;2019年至今在新利18彩票 药学院从事教学科研工作。主要从事绿色有机合成方法学、新药研发与合成工艺开发等相关研究工作。作为项目负责人主持国家自然科学基金青年项目、江苏省自然科学基金青年项目等;以通讯或第一作者在Chem. Commun.Org. Lett.Adv. Synth. Catal.Org. Chem. Front.J. Org. Chem.等发表论文二十余篇。

研究方向:

1. 绿色有机合成方法学

2. 药物合成新方法及新药研究与开发

科研项目:

2019.01-2021.12 国家自然科学基金青年项目(项目号:21801130),主持/完成

2018.07-2021.06 江苏省自然科学基金青年项目(项目号:BK20180689),主持/完成

2019.09-2020.02 新型端氰基键合剂中间体工艺放大研究(技术服务,横向),主要参与/完成

2019.06-2020.03 一种有机凝胶剂分子的中试工艺流程开发(技术服务,横向),主要参与/完成

2018.04-2028.04 NPFA等五个原料药的绿色合成工艺研发(技术服务,横向),主要参与/在研

代表性研究成果(近五年):

第一作者或通讯作者*发表的期刊论文

(1) Yu-Lin Zhai, Hui Zhou, Qing-Quan Liu, Bo-Rong Leng, Zixian Zhang, Jia-Zhuo Li, De-Cai Wang* andYi-Long Zhu*. Photocatalytic Markovnikov-type addition and cyclization of terminal alkynes leading to 4-sulfonyl quinoline-2(1H)-ones.Chem. Commun.,2022, 58, 5112-5115.

(2) Luan-Ying Li, Bo-Rong Leng, Jia-Zhuo Li, Qing-Quan Liu, Jianguang Yu,* Ping Wei, De-Cai Wang* andYi-Long Zhu*. Palladium-catalyzed regioselective hydrosulfonylation of allenes with sulfinic acids.RSC Adv.,2022,12, 8443-8448.

(3) Chi-Fan Zhu, Jie Zhang,Yi-Long Zhu,* Wen-Juan Hao, Shu-Jiang Tu, De-Cai Wang* and Bo Jiang*. A photoinduced arene–alkyne [3 + 2] cycloaddition cascade of 1-alkynylnaphthalen-2-ols for tunable synthesis of skeletally diverse bridged hexacycles.Org. Chem. Front.,2021,8, 1952-1958.

(4) Chi-Fan Zhu, Cong-Hui Gao, Wen-Juan Hao,Yi-Long Zhu,* Shu-Jiang Tu, De-Cai Wang* and Bo Jiang*. Synthesis of C3-alkylated benzofurans via palladium-catalyzed regiocontrolled hydro-furanization of unactivated alkenes.Org. Chem. Front.,2021, 8, 127-132.

(5) Hong-Ming Huang, Xu-Yan Wu, Bo-Rong Leng,Yi-Long Zhu,* Xin-Chao Meng, Yu Hong, Bo Jiang* and De-Cai Wang*. Cu(II)-Catalyzed formal [4+2] cycloaddition between quinone methides (QMs) and electron-poor 3-vinylindoles.Org. Chem. Front.,2020, 7, 414-419.

(6)Yi-Long Zhu, Chi-Fan Zhu, Peng Zhou, Wen-Juan Hao*, De-Cai Wang, Shu-Jiang Tu*, and Bo Jiang*. Pd(II)-Catalyzed Carbonyl-Directing Activation of Alkenes: Selective Fluorosulfonylation and Aminosulfonylation of 1,7-Enynes.J. Org. Chem.2018, 83, 9641-9653.

(7) Min-Hua Huang, Chi-Fan Zhu, Chun-Lan He,Yi-Long Zhu*, Wen-Juan Hao, De-Cai Wang*, Shu-Jiang Tu, Bo Jiang*. Visible-light-induced methylsulfonylation/bicyclization of C(sp3) tethered 1,7-enynes using DMSO/H2O system.Org. Chem. Front.2018, 5, 1643-1650.

(8)Min-Hua Huang,Yi-Long Zhu(Co-first author), Wen-Juan Hao, Ai-Fang Wang, De-Cai Wang*, Feng Liu, Ping Wei, Shu-Jiang Tu*, Bo Jiang*.Visible-Light Photocatalytic Bicyclization of 1,7-Enynes toward Functionalized Sulfone-Containing Benzo[a]fluoren-5-ones.Adv. Synth. Catal.2017, 359, 2229-2234.

(9)Yi-Long Zhu, Ai-Fang Wang, Jian-Yu Du, Bo-Rong Leng, Shu-Jiang Tu*, De-Cai Wang, Ping Wei*, Wen-Juan Hao and Bo Jiang*. Ag-Catalyzed difluorohydration ofβ-alkynyl ketones for diastereoselective synthesis of 1,5-dicarbonyl compounds.Chem. Commun.2017, 53, 6397-6400.(Inside Front Cover)

E-mail:zhuyilong_88@njtech.edu.cn

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