孙炳峰
新利18彩票 ,药学院,教授
研究领域
药物绿色高效合成,不对称合成,活性天然产物全合成
教育和研究经历
2019年-,新利18彩票 ,药学院,教授
2015-2017年,中科院上海有机化学研究所,研究员
2009-2015年,中科院上海有机化学研究所,副研究员
2005-2009年,先后在美国Indiana University和Brandeis University从事博士后研究
2000-2005年,中科院上海有机化学研究所,获理学博士学位
1996-2000年,南京大学应用化学系,获理学学士学位
获奖和荣誉
2018年入选江苏省“双创计划”
2016年获德国Thieme Chemistry Journals Award
2012年入选“中科院青年创新促进会”
近年主持和参与的部分项目
1)国家自然科学基金委,面上项目22071108 “战略合成子的可放大合成及在药物合成中的应用”;
2)国家自然科学基金委,面上项目21672243 “Arteminolides的不对称全合成研究”;
3)国家自然科学基金委,面上项目21472210 “几个活性二萜类海洋天然产物的不对称全合成研究”;
4)国家自然科学基金委,面上项目21172246 “复杂二萜Vinigrol的全合成研究”;
5)国家自然科学基金委,青年基金20902101 “Englerin A和Englerin B的全合成研究”;
6)中国科学院青年创新促进会专项;
7)教育部留学回国人员科研启动基金;
8)科技部973项目2010CB833206 “全新方法和策略的天然产物全合成”,参与;
9)国家自然科学基金委,重大研究计划“具有重要药用价值的多环天然产物高效合成”,参与。
讲授课程
生物活性化合物合成进展(研究生课程)
药物合成反应(本科课程)
近年发表论文目录
1.Gu, Q.; Wang, X.; Sun, B.,* Lin, G. “Grob-Fragmentation Enabled Approach to Clavulactone Analogues”Org. Lett.2019,21, 5082-5085.
2.Hou, H.; Gu, Q.; Wang, X.; Sun, D.-Q.; Sun, B.-F.* “Organocatalytic Asymmetric Synthesis of Cornolactones A and B, and Formal Synthesis of Brasoside and Littoralisone”Org. Chem. Front.2018,5, 358-360.
3.Xu, G.-Q.; Lin, G.-Q.; Sun, B.-F.* “Concise Asymmetric Total Synthesis of (−)-Patchouli Alcohol”Org. Chem. Front.2017,4, 2031-2033.
4.Wang, X.; Sun, W.-B.; Zou, J.-P.; Lin, G.-Q.; Sun, B.-F.* “Asymmetric Total Synthesis of Hedyosumin E aglycon, 7,10-Epoxyhedyosminolide andent-Zedolactone A”Org. Biomol. Chem.2016,14, 10581-10584.
5.Liu, L.; Zhou, S.;* Sun, B.* “Progresses in Total Synthesis of Platencin”Chin. J. Org. Chem.2016,36, 2091-2104.(review, in Chinese)
6.Fu, J.-G.; Shan, Y.-F.; Sun, W.-B.; Lin, G.-Q.; Sun, B.-F.* “An asymmetric approach to bicyclo[2.2.1]heptane-1-carboxylates via a formal [4+2] cycloaddition reaction enabled by organocatalysis”Org. Biomol. Chem.2016,14, 5229-32.
7.Sun, W.-B.; Wang, X.; Sun, B.-F.;* Zou, J.-P.; Lin, G.-Q. “Catalytic Asymmetric Total Synthesis of Hedyosumins A, B, and C”Org. Lett.2016,18, 1219-1221.
8.Fu, J.-G.; Xu, G.-Q.; Ding, R.; Lin, G.-Q.; Sun, B.-F.* “Asymmetric Total Synthesis of Lycopodium Alkaloids α-Obscurine,N-Desmethyl-α-obscurine, β-Obscurine and N-Desmethyl-β-obscurin”Org. Chem. Front.2016,3, 62-65.
9.Liu, J.; Zheng, H.-X.; Yao, C.-Z.; Sun, B.-F.; Kang, Y.-B.* “Pharmaceutical-Oriented Selective Synthesis of Mononitriles and Dinitriles Directly from Methyl(hetero)arenes: Access to Chiral Nitriles and Citalopram”J. Am. Chem. Soc.2016,138, 3294-3297.
10.Wang, J.; Sun, W.-B.; Li, Y.-Z.; Wang, X.; Sun, B.-F.*; Lin, G.-Q.; Zou, J.-P. “A Concise Formal Synthesis of Platencin”Org. Chem. Front.2015,2, 674-676.
11.Sun, B.-F.* “Total Synthesis of Natural and Pharmaceutical Products Powered by Organocatalytic Reactions”Tetrahedron Letters,2015,56, 2133-2140.
12.Li, Y.-Z.; Wang, J.; Sun, W.-B.; Shan, Y.-F.; Sun, B.-F.*; Lin, G.-Q.*; Zou, J.-P. “Enantioselective Synthesis of Bicyclo[2.2.2]octane-1-carboxylates under Metal Free Conditions”Org. Chem. Front.2015,2, 274-278.
13.Fu, J.-G.; Ding, R.; Sun, B.-F.*; Lin, G.-Q.* “Wagner-Meerwein Rearrangement of[3.3.1] BicyclicN-Boc Aminols: Vinyl Migration in Preference to Aryl Migration”Tetrahedron2014,70, 8374-8379.
14.Wang, X.-L.; Lu, Y.-Y.; Wang, J.; Wang, X.; Yao, H.-Q.; Lin, G.-Q.; Sun, B.-F.* “A Novel Synthetic Approach to the Bicyclo[5.3.1]undecan-11-one Framework of Vinigrol”Org. Biomol. Chem.2014,12, 3562-3566.(cover)
15.Ding, R.; Fu, J.-G.; Xu, G.-Q.; Sun, B.-F.*; Lin, G.-Q.* “Divergent Total Synthesis ofLycopodiumAlkaloidsHuperzine A, Huperzine B and Huperzine U”J. Org. Chem.2014,79, 240.
16.Wang, J.; Chen, S.-G.; Sun, B.-F.*; Lin, G.-Q.*; Shang, Y.-J. “Collective Total Synthesis of Englerin A, Englerin B, Orientalol E, Orientalol F, and Oxyphyllol: Application of the Organocatalytic [4+3] Cycloaddition Reaction”Chem. Eur. J.2013,19, 2539.
17.Wang, J.; Sun, B.-F.*; Cui, K.; Lin, G.-Q.* “An Efficient Total Synthesis of (-)-Epothilone B”Org. Lett.2012,14, 6354.
18.Ding, R.; Sun, B.-F.*; Lin, G.-Q.* “An Efficient Total Synthesis of (-)-Huperzine A”Org. Lett.2012,14, 4446.
19.Ding, R.; Lu, Y.-Y.; Yao, H.-Q.; Sun, B.-F.*; Lin, G.-Q.* “A New Approach to the Bicyclo[3.3.1]nonane Framework of Huperzine A-Like Molecules via Palladium-Catalyzed Intramolecular-Arylation”Science China Chemistry2012,55, 1097.
20.Lu, Y.; Yao, H.*; Sun, B.* “Progresses in Total Synthesis of Englerin A and Biological Evaluations of Its Analogues”Chin. J. Org. Chem.2012,32, 1.(review, cover, in Chinese)
21.Wang, C.-L.; Sun, B.-F.*; Chen, S.-G.; Ding, R.; Lin, G.-Q*; Xu, J.-Y.*; Shang, Y.-J. “Concise Formal Synthesis of (+)-Englerin A and Total Synthesis of (-)-Orientalol F: Establishment of the Stereochemistry of the Organocatalytic [4+3]-Cycloaddition Reaction”Synlett2012,23, 263.
22.Sun, B.*; Lin, G. “Natural Products and Medicinal Chemistry: A Review”Bulletin of the Chinese Academy of Sciences2011,Z1, 125.
23.Sun, B.-F.*; Wang, C.-L.; Ding, R.; Xu, J.-Y.; Lin, G.-Q.* “Concise Approach to the Core of Englerin A via an Organocatalytic [4+3] Cycloaddition Reaction”Tetrahedron Lett.2011,52, 2155.
发表著作章节
《天然产物全合成荟萃——抗生素及其他》吴毓林等,2012年,第十章 埃 坡霉素的全合成综述。
Strategies and Tactics in Organic Synthesis, ISBN: 9780128117903,ed. Michael Harmata, Vol 13, Chapter 6: Total synthesis of guaianoids through a strategy powered by organocatalytic [4+3] cycloaddition reactions.
电话:15618507338
邮箱:bfsun@njtech.edu.cn