主讲课程

现代分析方法，仪器分析

个人简介

李向玲，女，副教授，硕导。2015年毕业于南京大学化学化工学院化学专业，获理学博士学位；2015年-2017年于南京大学生命科学学院从事药学博士后研究工作。研究方向主要结合纳米材料和光学成像的优势，针对基因-细胞-活体等不同层面，系统建立生物功能分子的分析调控方法，解决生物环境领域中个性化探针构建、能量传递转换及微环境调控等技术难题。获江苏省“双创博士”资助，在Chemical Science、Analytical Chemistry、Chemical Communications、Lab on a Chip等杂志发表SCI论文30余篇，主持国家自然科学基金、省自然科学基金、中国博士后科学基金面上项目、江苏省高等学校面上项目、生命分析化学国家重点实验室开放基金等多项课题。

代表性成果

1.Lin-Lin Lu, Qin Zhang, Yu Gu,Xiang-Ling Li*, Jing Jing Xie*, Core-shell "loading-type" nanomaterials towards: Simultaneous imaging analysis of glutathione and microRNA.Anal. Chim. Acta, 2022, 1196, 339551.

2.Jin Wang, Qiao Yu,Xiang-Ling Li*, Xue-Li Zhao, Hong-Yuan Chen and Jing-Juan Xu*, A reversible plasmonic nanoprobe for dynamic imaging of intracellular pH during endocytosis,Chem. Sci., 2022, 13, 4893-4901.

3.Jin Wang , Dan Luo , Yandi Cai ,Xiang-Ling Li*, Hong-Yuan Chen, Jing-Juan Xu*, A plasmonic Au-Ag janus nanoprobe for monitoring endogenous hydrogen sulfide generation in living cells,Biosens. Bioelectron.2022, 213, 114422.

4.Jin Wang, Ying-Xue Liu,Xiang-Ling Li*, Hong-Yuan Chen, and Jing-Juan Xu*, Core-Shell Plasmonic Nanomaterials toward: Dual-Mode Imaging Analysis of Glutathione and Enhanced Chemodynamic Therapy,Anal. Chem.2021, 93, 10317-10325;

5.Mei-Rong Cui, Li-Xian Chen,Xiang-Ling Li*, Jing-Juan Xu*, Hong-Yuan Chen, NIR Remote-Controlled “Lock-Unlock” Nanosystem for Imaging Potassium Ions in Living Cells,Anal. Chem.2020, 92, 4558-4565;

6.Xue-Jiao Yang, Mei-Rong Cui,Xiang-Ling Li*,Hong-Yuan Chen, Jing-Juan Xu*, A Self-powered 3D DNA Walker with Programmability and Signal-amplification for Iluminating MicroRNA in Living Cells,Chem. Commun., 2020, 56, 2135-2138;

7.Jin Wang,Xiang-Ling Li*, Hong-Yuan Chen, Jing-Juan Xu*, “Loading-type” Plasmonic Nanoparticles for Detection of Peroxynitrite in Living Cells,Anal. Chem.2020, 92, 15647-15654;

8.Mei-Rong Cui,Xiang-Ling Li*, Hong-Yuan Chen, Jing-Juan Xu*,Smart Engineering of a Self-Powered and Integrated Nanocomposite for Intracellular MicroRNA Imaging,CCS Chem.2020, 2, 2063-2073;

9.Mei-Rong Cui,Xiang-Ling Li*, Jing-Juan Xu*, Hong-Yuan Chen, Target-triggered, Self-powered DNAzyme-MnO₂Nanosystem: towards Imaging MicroRNAs in Living Cells,Chem. Commun.,2019, 55, 13366-13369;

10.Ting-Ting Zhang, Cong-Hui Xu, Wei Zhao, Yu Gu,Xiang-Ling Li*, Jing-Juan Xu*, Hong-Yuan Chen, A Redox-activated Theranostic Nanoagent: toward Multi-mode Imaging Guided Chemo-photothermal Therapy,Chem. Sci.,2018, 9, 6749-6757.